RNAi Controls
Genscript Corporation ROR1 hFc Chimera Human/Cynomo
ROR1 (Receptor tyrosine kinase-like orphan receptor 1) also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1) is a member of the ROR family within receptor tyrosine kinases (RTK) superfamily Two ROR family members (ROR1 and ROR2) have been identified and are characterized by the intracellular tyrosine kinase domains highly related to those of the Trk-family receptor tyrosine kinases and by the extracellular Frizzled-like cysteine-rich domains and kringle domains which are common to receptors of the Wnt family members
Genscript Corporation IL-17R alpha/CD217 hFc Chimera
Interleukin 17 (also known as CTLA 8) is a T cell expressed pleotropic cytokine IL 17 binds to IL 17 receptor (IL 17 R) which shares no homology with any known family of receptors While the expression of IL 17 is restricted to activated T cells the IL 17 R mRNA exhibits a broad tissue distribution and has been detected in virtually all cells and tissues tested The human IL 17 R gene was localized to chromosome 22
Genscript Corporation IL-17R alpha/CD217 hFc Chimera
Interleukin 17 (also known as CTLA 8) is a T cell expressed pleotropic cytokine IL 17 binds to IL 17 receptor (IL 17 R) which shares no homology with any known family of receptors While the expression of IL 17 is restricted to activated T cells the IL 17 R mRNA exhibits a broad tissue distribution and has been detected in virtually all cells and tissues tested The human IL 17 R gene was localized to chromosome 22
Genscript Corporation CD30/TNFRSF8 hFc Chimera Huma
The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153 TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in subpopulations of activated T-and B-cells in nonpathologic conditions CD30 expression is upregulated in various hematological malignancies including Reed-Sternberg cells in Hodgkin s disease (HD) anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin s lymphomas (NHLs)
Medchemexpress LLC Robo1 recombinant protein (rat, HEK293, C-terminal His tag) | 10UG
Recombinant rat ROBO1 receptor protein produced in HEK293 cells with a C-terminal His tag. The product is glycosylated and purified to high quality, making it suitable for binding, structural, and biochemical studies. Supplied as 10 μg with an approximate molecular weight of 70-95 kDa and >95% purity. Store at -20°C and aliquot for extended storage; after reconstitution it is stable at 4°C for short-term use.
Genscript Corporation CD47 hFc Chimera Mouse
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRP ) CD-47 acts as a don t eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers
Genscript Corporation CD37 hFc Chimera Human
CD37 is a tetraspanin expressed prominently on the surface of B cells It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia Currently several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials Given the unique role of CD37 in the biology of B cells it seems that CD37 constitutes more than a docking point for monoclonal antibodies and targeting this molecule may provide additional benefit to relapsed or refractory patients
Genscript Corporation CD3ECD3G hFc Chimera Biotin
T-cell surface glycoprotein CD3 epsilon CD3 gamma chain also known as CD3E CD3G are single-pass type I membrane proteins When antigen presenting cells (APCs) activate T-cell receptor (TCR) TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D CD3E CD3G and CD3Z All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain
Genscript Corporation CD27/TNFRSF7 hFc Chimera Huma
CD27 also known as TNFRSF7 is an approximately 55 kDa transmembrane protein in the TNF receptor superfamily It functions as a co stimulatory molecule that supports lymphocyte activation and survival It binds to ligand CD70 and plays a key role in regulating B-cell activation and immunoglobulin synthesis
Genscript Corporation CD52 mFc Chimera Human
CD52 also known as CAMPATH-1 antigen HE5 and gp20 is a cell surface glycoprotein that can be targeted to induce immune suppression by complement-mediated cell lysis Mature human CD52 is a 12 amino acid peptide that is tethered to the cell surface with a GPI linkage CD52 may play a role in carrying and orienting carbohydrate as well as having a more specific role
STA PHARMACEUTICAL US LLC DNA A(Bz) amidite | 1 g | CAS 98796-53-3 | MDL MFCD00036314
DNA A(Bz) amidite is a Amidite reagent (Subcategory: Adenine Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 98796-53-3
- MDL: MFCD00036314
- InChIKey: GGDNKEQZFSTIMJ-AKWFTNRHSA-N
- Molecular Weight: 857.948761998
- Molecular Formula: C47H52N7O7P
- Purity: ≥99%
- Container Type: 60 mL Glass (Septum)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 38.3 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3S,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1C[C@H](N2C3=C(N=C2)C(NC(C4=CC=CC=C4)=O)=NC=N3)O[C@@H]1COC(C5=CC=C(C=C5)OC)(C6=CC=C(C=C6)OC)C7=CC=CC=C7)OCCC#N)C(C)C)C
Genscript Corporation CD40/TNFRSF5 hFc Chimera Huma
CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects CD40 molecule is a potential target for cancer immunotherapy There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells
Genscript Corporation CD52 hFc Chimera Mouse
CD52 also known as CAMPATH-1 antigen HE5 and gp20 is a cell surface glycoprotein that can be targeted to induce immune suppression by complement-mediated cell lysis Mature human CD52 is a 12 amino acid peptide that is tethered to the cell surface with a GPI linkage CD52 may play a role in carrying and orienting carbohydrate as well as having a more specific role
Refrigiwear Inc. Iron Tuff Snap-on Hood
Complete your protection by adding the Iron-Tuff Snap-On Hood to your Iron-Tuff jacket. Headwear is vital to keeping warm. Extend your -50°F protection with the same Iron-Tuff warmth, toughness and durability you already know and trust.
STA PHARMACEUTICAL US LLC DNA A(Bz) amidite | 10 g | CAS 98796-53-3 | MDL MFCD00036314
DNA A(Bz) amidite is a Amidite reagent (Subcategory: Adenine Series) sold by WuXi TIDES. Offered in 10 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 98796-53-3
- MDL: MFCD00036314
- InChIKey: GGDNKEQZFSTIMJ-AKWFTNRHSA-N
- Molecular Weight: 857.948761998
- Molecular Formula: C47H52N7O7P
- Purity: ≥99%
- Container Type: 250 mL Glass (28-400)
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 179.7 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3S,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1C[C@H](N2C3=C(N=C2)C(NC(C4=CC=CC=C4)=O)=NC=N3)O[C@@H]1COC(C5=CC=C(C=C5)OC)(C6=CC=C(C=C6)OC)C7=CC=CC=C7)OCCC#N)C(C)C)C