RNAi Controls
Genscript Corporation CD300LF hFc Chimera Human
Murine norovirus (MNoV) is an important model of human norovirus (HNoV) and mucosal virus infection more broadly CD300lf as a proteinaceous receptor for MNoV Interestingly its paralogue CD300ld was also sufficient for MNoV infection in vitro CD300lf is essential for both oral and parenteral MNoV infection and to elicit anti-MNoV humoral responses in vivo human CD300lf (huCD300lf) is not essential for HNoV infection nor does huCD300lf inhibit binding of HNoV virus-like particles to glycans
Genscript Corporation PD-L1 Fc Chimera Mouse
Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene PD-L1 is a 40 kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy tissue allografts autoimmune disease and other disease states such as hepatitis Normally the immune system reacts to foreign antigens where there is some accumulation in the lymph nodes or spleen which triggers a proliferation of antigen-specific CD8 T cell The formation of PD-1 receptor / PD-L1 or B7 1 receptor /PD-L1 ligand complex transmits an inhibitory signal which reduces the proliferation of these CD8 T cells at the lymph nodes and supplementary to that PD-1 is also able to control the accumulation of foreign antigen specific T cells in the lymph nodes through apoptosis which is further mediated by a lower regulation of the gene Bcl-2 PD-L
HORIZON DISCOVERY BIOSCIENCES LIMITED SMARTVECTOR INDUCIBLE NON-TARG
NC1122059 SMARTVECTOR INDUCIBLE NON-TARG
Abnova™ CD44 Pre-design Chimera RNAi
Homo sapiens CD44 antigen (homing function and Indian blood group system) (CD44), transcript variant 8, mRNA.
Abnova™ ROBO1 Pre-design Chimera RNAi
Homo sapiens roundabout, axon guidance receptor, homolog 1 (Drosophila) (ROBO1), transcript variants, mRNA. This product targets for all of 3 transcript variants (NM_001145845.1,NM_002941.3,NM_133631.3)
Abnova™ ROBO2 Pre-design Chimera RNAi
Homo sapiens roundabout, axon guidance receptor, homolog 2 (Drosophila) (ROBO2), transcript variants mRNA. This product targets for all of 5 transcript variants (NM_001128929,NM_001290039,NM_001290040,NM_001290065,NM_002942)
Abnova™ ACLY Pre-design Chimera RNAi
Homo sapiens ATP citrate lyase (ACLY), transcript variants, mRNA